Overcoming Challenges in Ophthalmic Drug Delivery including Bioavailability and Sterility

Overcoming Challenges in Ophthalmic Drug Delivery including Bioavailability and Sterility

What’s In This Video Webinar

Delivery of therapeutics to the human eye is one of the most interesting—but challenging—endeavors a formulator can take on. The anatomy and chemical composition of the eye makes it highly resistant to pharmaceutical penetration. Successfully circumventing these protective barriers requires intimate knowledge of ocular delivery as well as specialized development and manufacturing expertise.

This webcast explores solutions to some of today’s most challenging issues in ophthalmic drug delivery including a selection of dosage form, options for increasing bioavailability, improving drug stability, properly handling highly potent APIs, overcoming patient compliance issues, and meeting the sterility critical quality attribute.

View The Video Webinar

Insoluble APIs Scaring You? Don’t Be Afraid of Nanotechnology!

Insoluble APIs Scaring You? Don’t Be Afraid of Nanotechnology!

What’s In This Video Webinar

Nanotechnology, the manipulation of materials at the nanometer length scale, sounds like daunting sci-fi, but in practice provides the pharmaceutical product developer with a host of options to protect a labile drug molecule, improve the bioavailability of a drug, target a drug to specific tissues or cells, or simply offer a reformulation option to manage the lifecycle of an existing product.

This webcast explores the most common nanotechnologies practices for pharmaceutical formulation development, the pros and cons of each approach, which types of molecules can be incorporated and how, specific manufacturing equipment, characterization, and regulatory considerations.

View The Video Webinar

What’s In This Video Webinar

A growing number of APIs suffer from poor water solubility, low bioavailability, and insufficient stability. As more BCS class II­–IV compounds enter the drug development pipeline, formulators must look to advanced drug delivery systems to achieve a desired therapeutic effect and protect APIs from degradation. Long-acting dosage forms such as microparticle depot injections and implantable systems—both biodegradable and biodurable—offer tunable designs that help overcome these challenges. However, successful development and optimization of these complex drug products require specialized knowledge, equipment, and facilities to properly execute.

This webinar explores key considerations in developing long-acting drug products, including a comparison of design options, polymers, and manufacturing methods for both depots and implants. Experts investigate some of the common challenges in these areas and explain how long-acting dosage forms are characterized by real-world case studies.

View The Video Webinar