Particle Sciences, Inc. (PSI), located in Bethlehem, PA, is a full-service CRO specializing in nano-based and rational solubility systems design approaches to formulation. PSI brings this skill set to bear on all dosage forms ranging from oral to parenteral to topical and drug/device combinations. In addition to industry-leading formulation capabilities, PSI has GLP/GMP analytic, bioanalytic, and characterization labs and class 100 clean room facilities. Providing an integrated suite of services aimed at minimizing the time and risks of drug development, PSI is expert in fine-particle and nanotechnology approaches and regularly deals with challenging APIs, high-potency compounds, and controlled substances. They work with a variety of APIs, including small molecules, peptides, proteins, and oligos. The company brings 2 decades of expertise providing an expansive suite of preformulation, formulation, analytic, and GLP/GMP manufacturing services – including sterile products. A responsive and collaborative approach ensures the objectives of all clients, large and small, are successfully met on-time and on-budget with the highest degree of quality.
The HORIBA Group of worldwide companies provides an extensive array of instruments and systems for applications ranging from automotive R&D, process and environmental monitoring, in vitro medical diagnostics, semiconductor manufacturing, and metrology, to a broad range of scientific R&D and QC measurements. Proven quality and trustworthy performance have established widespread confidence in the HORIBA Brand. HORIBA’s current R&D efforts are directed toward nanotechnology instrumentation and its application to the field of Life Sciences. From Microscopic Raman Imaging to Fluorescence Spectroscopic mapping to miniaturized Water Quality measurements, the analysis of small, biological materials is a key focus. In the area of Particle Characterization products, a number of new technologies have been introduced to support industrial R&D initiatives. One recent example would be Dynamic Light Scattering (DLS) for the determination of size and Zeta Potential for small particles in dilute systems. Acoustic spectroscopy is also offered for similar types of measurements in more concentrated samples. Both Static and Dynamic Image Analysis has been developed to provide size and shape information for small particles in wet and dry systems. This provides a nice arsenal of weapons to characterize particles that are of major concern to the Life Sciences Industry.
Specialty Pharma recently spoke with Robert Lee, PhD, Vice President of Pharmaceuticals and Quality, Particle Sciences, and Michael C. Pohl, PhD, Vice President, Horiba Instruments, Inc. to discuss their recent strategic alliance to provide their clients with the most up-to-date physical characterization tools with operational expertise in a fully GLP/GMP-compliant setting.