There are now more than 33 million people infected with HIV/AIDS worldwide and in 2008 there were 2.7 million new infections. These daunting numbers have pushed researchers to focus more on finding prevention methods. Since the HIV/AIDS pandemic affects every region around the world, it has united researchers and institutions in the fight to prevent HIV. Microbicides, products that can be applied topically to reduce the risk of HIV transmission during sexual intercourse, are the focus of intensive study. Research in this field has just received a considerable boost from the success of a clinical trial of one of the new generation microbicides announced at the 17th International AIDS Conference held in Vienna.